University of British Columbia

Research Spotlight

Publication Highlights

Geoffrion, Roxana MD*; Koenig, Nicole A. BA*; Zheng, Meimuzi MSc*; Sinclair, Nicholas BSc*; Brotto, Lori A. PhD*; Lee, Terry PhD†; Larouche, Maryse MD MPH‡ Preoperative Depression and Anxiety Impact on Inpatient Surgery Outcomes, Annals of Surgery: March 2021 - Volume 2 - Issue 1 - p e049 doi: 10.1097/AS9.0000000000000049

Roxana Geoffrion, Obstetrics and Gynecology Associate Professor at the University of British Columbia and team aimed to quantify the association of pre-operative depression and anxiety symptoms on postoperative complications and to explore sex differences and sex-specific coping mechanisms in patients undergoing major surgery. They conducted a prospective cohort study of depression and anxiety symptoms using several validated questionnaires in patients undergoing major surgery and the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines. Postoperative data collection included a visual analogue scale for pain, narcotic use, post-op complications, length of stay, and readmissions. Pre-operative depression, anxiety and coping mechanisms were associated with adverse surgical outcomes and postoperative pain, with females significantly more impacted than males. Their work also highlighted the use of validated, brief questionnaires that can be easily used in the clinical setting and the importance of holistic pre-operative medical care and patient education. In addition, sleep and exercise emerged as novel therapeutic targets to optimize outcomes for patients undergoing major surgery. Congratulations to Dr Geoffrion and team on publishing one of the largest prospective cohort investigations of mental health in both sexes with recruitment from various surgical specialties in the Annals of Surgery.

2020-2021 Publication List

Moreira Vasconcelos CT, Silva Gomes ML, Geoffrion R, Saboia DM, de Castro Bezerra K, Vasconcelos Neto JA. Pessary evaluation for genital prolapse treatment: from acceptance to successful fitting. Neurourology and Urodynamics. 2020 Nov;39(8):2344-2352.

Harvey MA, Chih HJ, Geoffrion R, Amir B, Bhide A, Miotla P, Rosier PFWM, Offiah I, Pal M, Alas AN. International Urogynecology Consultation Chapter 1 Committee 5: relationship of pelvic organ prolapse to associated pelvic floor dysfunction symptoms: lower urinary tract, bowel, sexual dysfunction and abdominopelvic pain.Int Urogynecol J. 2021 Oct;32(10):2575-2594. doi: 10.1007/s00192-021-04941-5. Epub 2021 Aug 2.PMID: 34338825.

Larouche M, Belzile E, Geoffrion R. Surgical Management of Symptomatic Apical Pelvic Organ Prolapse: A Systematic Review and Meta-analysis. Obstet Gynecol. 2021 Jun 1;137(6):1061-1073. doi: 10.1097/AOG.0000000000004393.PMID: 33957652.

Zhang BY, Wong JMH, A Koenig N, Lee T, Geoffrion R. Risk factors for urinary retention after urogynecologic surgery: A retrospective cohort study and prediction model. Neurourol Urodyn. 2021 Jun;40(5):1182-1191. doi: 10.1002/nau.24676. Epub 2021 Apr 23.PMID: 33891339.

Gong M, Mann GK, Koenig N, Geoffrion R. Documenting Perineal and Obstetrical Anal Sphincter Injury Care at Childbirth: A Cross-Sectional Study. J Obstet Gynaecol Can. 2021 Oct;43(10):1164-1169. doi: 10.1016/j.jogc.2021.02.120. Epub 2021 Mar 6.PMID: 33684531.

Geoffrion R, Larouche M. Guideline No. 413: Surgical Management of Apical Pelvic Organ Prolapse in Women. J Obstet Gynaecol Can. 2021 Apr;43(4):511-523.e1. doi: 10.1016/j.jogc.2021.02.001. Epub 2021 Feb 3.PMID: 33548503.

Geoffrion R, Larouche M. Directive clinique no 413 : Traitement chirurgical du prolapsus génital apical chez les femmes. J Obstet Gynaecol Can. 2021 Apr;43(4):524-538.e1. doi: 10.1016/j.jogc.2021.02.002. Epub 2021 Feb 3.PMID: 33548502.

Geoffrion R, Yang EC, Koenig NA, Brotto LA, Barr AM, Lee T, Allaire C, Bedaiwy MA, Yong P. Recreational Cannabis Use Before and After Legalization in Women With Pelvic Pain. J.Obstet Gynecol. 2021 Jan 1;137(1):91-99. doi: 10.1097/AOG.0000000000004207.PMID: 33278297.

Stothers L, Locke JA, Abdulaziz M, Lazare D, Kavanagh A, Macnab A. Standing open magnetic resonance imaging improves detection and staging of pelvic organ prolapse. Can Urol Assoc J. 2021 Aug 26. doi: 10.5489/cuaj.7244. Online ahead of print.PMID: 34464248.

Brennand EA, Wu G, Houlihan S, Globerman D, Gagnon LH, Birch C, Hyakutake M, Carlson KV, Al-Shankiti H, Robert M, Lazare D, Kim-Fine S; Calgary Women's Pelvic Health Research Group. Two Intraoperative Techniques for Midurethral Sling Tensioning: A Randomized Controlled Trial. Obstet Gynecol. 2020 Sep;136(3):471-481. doi: 10.1097/AOG.0000000000004027.PMID: 32769657 Free PMC article. Clinical Trial.

Walter JE, Brennand EA, Lemos N, Cundiff GW; Canadian Society of Pelvic Medicine Mesh Complications Writing Group. Corrigendum to 'Canadian Society of Pelvic Medicine Response to the Collège des Médecins du Québec Rapport d'Enquête' [Journal of Obstetrics and Gynaecology Canada 43/3 (2021) 298-299]. J Obstet Gynaecol Can. 2021 May;43(5):650. doi: 10.1016/j.jogc.2021.03.008.PMID: 33992128 No abstract available.

Walter JE, Brennand EA, Lemos N, Cundiff GW; Canadian Society of Pelvic Medicine Mesh Complications Writing Group. Letter: Canadian Society of Pelvic Medicine Response to the Collège des Médecins du Québec Rapport d'Enquête. J Obstet Gynaecol Can. 2021 Mar;43(3):298-299. doi: 10.1016/j.jogc.2020.10.004.PMID: 33640099 No abstract available.

Cundiff GW. Le Collège des médecins du Québec devrait-il déterminer l'utilisation adéquate des bandelettes sous-urétrales au Canada? Une analyse du rapport d'enquête. J Obstet Gynaecol Can. 2021 Mar;43(3):285-287. doi: 10.1016/j.jogc.2021.01.007.PMID: 33640096 No abstract available.

Cundiff GW. Should the Collège des Médecins du Québec Determine How Mid-Urethral Slings Are Used in Canada? A Review of the Rapport d'Enquête. J Obstet Gynaecol Can. 2021 Mar;43(3):283-284. doi: 10.1016/j.jogc.2020.09.014.PMID: 33640095 No abstract available.

Chen I, Mallick R, Allaire C, Bajzak KI, Belland LM, Bougie O, Cassell KA, Choudhry AJ, Cundiff GW, Kroft J, Leyland NA, Maheux-Lacroix S, Rajakumar C, Randle E, Robertson D, Thiel JA, Tulandi T, Yong PJ, Laberge PY; Canadian Women's Investigators for Surgical Excellence in Research (CanWISER) Collaboration.J Technicity in Canada: A Nationwide Whole-Population Analysis of Temporal Trends and Variation in Minimally Invasive Hysterectomies. Minim Invasive Gynecol. 2021 May;28(5):1041-1050. doi: 10.1016/j.jmig.2021.01.010. Epub 2021 Jan 18.PMID: 33476750. 10.1002/ijgo.13441. Epub 2020 Dec 8. PMID: 33112417.

Larouche M, Albert AYK, Lipsky N, Walmsley S, Loutfy M, Smaill F, Trottier S, Bitnun A, Yudin MH, Cundiff GW, Money DM. Urinary symptoms and quality of life in women living with HIV: a cross-sectional study. Int Urogynecol J. 2021 Feb;32(2):353-358. doi: 10.1007/s00192-020-04343-z. Epub 2020 May 22.PMID: 32440885.